Innovation represents a source of growth and profitability for firms in today's globalizing competitive environment. In particular, radical innovations are gaining in importance for large established companies as they can be considered a source of organizational rejuvenation. Some large companies organize for radical innovations by establishing dedicated organizational structures. The present study provides a common basis for these activities drawing upon research in the field of radical innovation management and corporate entrepreneurship, which are integrated in a new definitional framework of “New Business Creation” (NBC). In six in-depth case studies and a cross-case analysis, Theo Fowinkel explores the management of human resources in NBC as the commitment, enthusiasm, and self-motivation of employees significantly affects the development of radical innovation.  Contents NBC case studies HRM systems in an NBC context (cross-case analysis) Target Groups Researchers and students of business administration, innovation management, human research management Manager, innovation manager, human research manager The Author Theo Fowinkel studied mechanical engineering and business administration at the Berlin Institute of Technology (TU Berlin) and holds a Diplôme de Grande École through a dual degree program from ESCP Europe (Paris). He worked in the field of mergers & acquisitions in Frankfurt and as a strategy consultant in Berlin.