This book constitutes the proceedings of the 14th International Conference on Smart Homes and Health Telematics, ICOST 2016, held in Wuhan, China, in May 2016. The 39 regular papers, 5 short papers and 1 poster paper included in this volume were carefully reviewed and selected from 83 submissions. They were organized in topical sections named: smart homes, smart urban spaces and new assistive living space concepts in the smart city; e-health for future smart cities; context awareness and autonomous computing; home networks and residential gateways; middleware support for smart homes and health telematic services; e-health and chronic disease management; e-health technology assessment and impact analysis; tele-assistance and tele-rehabilitation; modeling of physical and conceptual information in intelligent environments; medical big data collection, processing and analysis; human machine interfaces; wearable sensors and continuous health monitoring; social, privacy and security issues; mobile health services; and smart rehabilitation technologies.