This book contains all refereed papers that were accepted to the fifth edition of the « Complex Systems Design & Management » (CSD&M 2014) international conference which took place in Paris (France) on the November 12-14, 2014. These proceedings cover the most recent trends in the emerging field of complex systems sciences & practices from an industrial and academic perspective, including the main industrial domains (aeronautic & aerospace, transportation & systems, defense & security, electronics & robotics, energy & environment, health & welfare services, software & e-services), scientific & technical topics (systems fundamentals, systems architecture & engineering, systems metrics & quality, systemic tools) and system types (transportation systems, embedded systems, software & information systems, systems of systems, artificial ecosystems). The CSD&M 2014 conference is organized under the guidance of the CESAMES non-profit organization, address: CESAMES, 8 rue de Hanovre, 75002 Paris, France.  .