This book explores a range of critical issues and emerging topics relevant to the linkages between information technologies and organizational systems. It encourages debate and opens up new avenues of inquiry in the fields of Information Systems, organization and management studies by investigating selected themes of growing research interest from multiple disciplinary perspectives such as organizational innovation and impact, information technology, innovation transfer, and knowledge management. The volume is divided into two sections, each of which focuses on a specific theme: ICT, organizational innovation and change; and ICT and knowledge management. The content of each section is based on a selection of the best papers (original double-blind peer-reviewed contributions) presented at the annual conference of the Italian chapter of the AIS, held in Genoa, Italy in November 2014.