This book constitutes the refereed proceedings of the 19th International Conference on Engineering Applications of Neural Networks, EANN 2018, held in Bristol, UK, in September 2018. The 16 revised full papers and 5 revised short papers presented were carefully reviewed and selected from 39 submissions. The papers are organized in topical sections on activity recognition, deep learning, extreme learning machine, machine learning applications, predictive models, fuzzy and recommender systems, recurrent neural networks, spiking neural networks.