This book constitutes the refereed proceedings of the 15th International Conference entitled Beyond Databases, Architectures and Structures, BDAS 2019, held in Ustroń, Poland, in May 2019. It consists of 26 carefully reviewed papers selected from 69 submissions. The papers are organized in topical sections, namely big data and cloud computing; architectures, structures and algorithms for efficient data processing and analysis; artificial intelligence, data mining and knowledge discovery; image analysis and multimedia mining; bioinformatics and biomedical data analysis; industrial applications; networks and security. .