Introduction -- Part I: The Field Of Community Informatics Design Science: Digital Social Systems’ Theoretical Foundations -- Universal Anteriorities and Third Phase Science -- Community Informatics Design’s Theoretical Basis -- Community Informatics Design in Action: Towards Operational Ways of Thinking in Order to Start a Design Process -- Generic Communication and Community Informatics Design: Evaluation and Validation of Socio-Technical Design of a Universal Communication Platform, the Informatics Design Assistance System, Using the CAPACITÉS Evaluation Model -- Towards a Scientific Collaborative Design Approach: The Construction of a Community Informatics Design Assistance System to Support Communities and Virtual Organizations -- Part II: From Modeling to Implantation the Reference Framework, Instantiation Methodology and the Discovery and Strategic Alignment Matrices -- Reference Model, Governance Framework, and Instantiation Strategy -- An Instantiation Methodology and its Multiple Aspects -- The Discovery and Strategic Alignment Matrices for Socio-Technical Systems’ Design -- The Fields and the Definition Taken Into Account for the Construction of the Multimodal and Multi-Aspect Discovery and Strategic Alignment Matrices (2MDSAM) for the DSS Design -- The Organization and Governance of an Incubation and Learning Environment with the Help of Tool Boxes: Reference Model, Community Informatics Design Framework and Instantiation Methodology -- The Conclusion: Towards a Computerized Modeling Tool for a 2MDSAM with Fully Qualified and Assigned Functionalities.