Part I: Preliminaries -- Anticipating the Big Picture: Some Clues -- Chemical and Notational Preliminaries -- Reaction Networks, Kinetics, and the Induced Differential Equations -- Open Systems: Why Study Nonconservative and Otherwise Peculiar Reaction Networks? -- A Toy-Reaction-Network Zoo: Varieties of Behavior and Some Questions -- Part II: Some Principle Theorems: A First Look -- Aspects of Reaction Network Structure -- The Deficiency Zero Theorem -- Deficiency One Theory -- Concentration Robustness and Its Importance in Biology: Some More Deficiency-Oriented Theorems -- Concordant Reaction Networks: Architectures that Promote Dull, Reliable Behavior Across Broad Kinetic Classes -- The Species-Reaction Graph -- The Big Picture Revisited -- Part III: Going Deeper -- Quasi-Thermodynamic Kinetic Systems -- Detailed Balancing -- Complex Balancing -- Deficiency Zero Theory Foundations and Some Key Propositions -- Deficiency One Theory Foundations -- Concentration Robustness Foundations -- Species-Reaction Graph Foundations.