Determining the value of an information system for an organization is challenging, especially before the execution of the project in which the system is put into operation. Many organizations find it challenging to identify the potential benefits of the investment, while even more have difficulties with their quantification. An analysis, in which multiple possible investments and approaches are compared with respect to their benefits, costs and risks, is called a ‘business case’. The current frameworks that can be used to develop business cases offer too little support for the aforementioned challenges. The author explores opportunities to improve business case frameworks, and thereby the efficiency and effectiveness of business case development.   Contents   ·         Challenges in Business Case Development ·         Requirements for Business Case Frameworks ·         Business Case Ontology ·         Reuse in Business Case Development     Target Groups ·         Researchers, teachers and students in the field of business informatics and management accounting ·         Business case developers, decision makers ·         Developers of business case software   The Author Dr. Bart-Jan van Putten obtained his doctorate degree at the Humboldt University of Berlin, Institute of Information Systems, under the supervision of Prof. Oliver Günther, PhD.