This book constitutes the proceedings of the 13th International Symposium on Advanced Parallel Processing Technologies, APPT 2019, held in Tianjin, China, in August 2019. The 11 full papers presented in this volume were carefully reviewed and selected from 35 submissions. The papers are organized in topical sections named: System Support for Neural Networks; Scheduling and File Systems; Optimization and Parallelization; Security and Algorithms.