This book constitutes the refereed conference proceedings of the First International Conference on Ambient Intelligence for Health, AmIHEALTH 2015, held in Puerto Varas, Chile, in December 2015. The 20 revised full papers and 9 short papers were reviewed and selected from 32 submissions and cover topics on technologies for implementing AmIHealth environments; frameworks related with AmIHealth environments; applied algorithms in e-Health systems; interactions within the AmIHealth environments; applications and case studies of AmIHealth environments; and metrics for health environments.