The two-volume set LNAI 10841 and LNAI 10842 constitutes the refereed proceedings of the 17th International Conference on Artificial Intelligence and Soft Computing, ICAISC 2018, held in Zakopane, Poland in June 2018. The 140 revised full papers presented were carefully reviewed and selected from 242 submissions. The papers included in the first volume are organized in the following three parts: neural networks and their applications; evolutionary algorithms and their applications; and pattern classification.