This book constitutes revised selected papers from the 6th International Conference on Information Systems, Logistics, and Supply Chains, ILS 2016, held in Bordeaux, France, in June 2016. The conference deals with topics related to supply chain design and management, information and decision-making systems, and innovative practices in logistics. It also encompasses issues such as sustainability, societal impact, uncertainty, and collaboration in supply chain management. The 13 full papers presented were carefully reviewed and selected for inclusion in this volume and reflect the diverse challenges and opportunities experienced in logistics, information and supply chain management. They were organized in topical sections named: transportation and logistics; supply chain planning; collaboration and operations in supply chain; and applications of supply chain topics to business environments (case studies). .