Computational Methods for Processing and Analysis of Biological Pathways
tarafından
Bezerianos, Anastasios. author.
Başlık
:
Computational Methods for Processing and Analysis of Biological Pathways
Yazar
:
Bezerianos, Anastasios. author.
ISBN
:
9783319538686
Yazar
:
Bezerianos, Anastasios. author.
Edisyon
:
1st ed. 2017.
Fiziksel Niteleme
:
VIII, 87 p. 11 illus. in color. online resource.
Seri
:
SpringerBriefs in Computer Science,
İçindekiler
:
Introduction -- Networks and Pathways in Systems Pharmacology -- Time Varying Methods for Pathway and Sub-Pathway Analysis -- Identification of Differentially Expressed Pathways and Sub-Pathways.
Özet
:
This work offers a guided walkthrough of one of the most promising research areas in modern life sciences, enabling a deeper understanding of involved concepts and methodologies via an interdisciplinary view, focusing on both well-established approaches and cutting-edge research. Highlighting what pathway analysis can offer to both the experimentalist and the modeler, the text opens with an introduction to a general methodology that outlines common workflows shared by several methods. This is followed by a review of pathway and sub-pathway based approaches for systems pharmacology. The work then presents an overview of pathway analysis methods developed to model the temporal aspects of drug- or disease-induced perturbations and extract relevant dynamic themes. The text concludes by discussing several state-of-the-art methods in pathway analysis, which address the important problem of identifying differentially expressed pathways and sub-pathways.
Konu Başlığı
:
Bioinformatics.
Biological models.
Computational Biology/Bioinformatics. http://scigraph.springernature.com/things/product-market-codes/I23050
Systems Biology. http://scigraph.springernature.com/things/product-market-codes/L15010
Yazar Ek Girişi
:
Dragomir, Andrei.
Balomenos, Panos.
Ek Kurum Yazar
:
SpringerLink (Online service)
Elektronik Erişim
:
Materyal Türü | Barkod | Yer Numarası | Durumu/İade Tarihi |
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Electronic Book | 222359-1001 | QH324.2 -324.25 | Springer E-Book Collection |