This book constitutes the refereed proceedings of the 10th International Conference on Collaboration Technologies, CollabTech 2018, held in Costa de Caparica, in September 2018. The 12 full papers presented in this book together with 4 short papers were carefully reviewed and selected from 36 submissions. The papers focus on topics such as: Communication Enhancement, Inter-Cultural Collaboration, Learning Support System, Entertainment System, Social Studies, and UI and UX.